Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994977 | 0.97 | TSHR (0.50) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL10780923 | 0.97 | TSHR (0.50) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL11327302 | 0.97 | TSHR (0.50) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL932358 | 0.90 | TSHR (0.40) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL9746087 | 0.88 | TSHR (0.39) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL9745452 | 0.78 | — | — | |
| SCHEMBL9745220 | 0.78 | TSHR (0.35) | TSHRTHRBSMN1; SMN2EPHX1LMNA | |
| SCHEMBL30815981 | 0.78 | TSHR (0.50) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1405421 | 0.78 | TSHR (0.50) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7899288 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |