Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28961387 | 0.80 | GRIN2D (0.48) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL29588654 | 0.80 | GRIN2D (0.48) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL27676943 | 0.78 | GRIN2D (0.49) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL9445575 | 0.77 | RPS6KA3 (0.36) | KDM4EMAPTPOLBAHRSMN1; SMN2 | |
| SCHEMBL28271350 | 0.74 | AHR (0.37) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL29955981 | 0.74 | MAPT (0.49) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| Phosphine SCHEMBL27478320 | 0.73 | AHR (0.35) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL8687440 | 0.72 | GPR17 (0.50) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL3604992 | 0.72 | GPR17 (0.61) | KDM4EMAPTPOLBGRIN2DGRIN3B | |
| SCHEMBL10022730 | 0.72 | GRIN2D (0.42) | KDM4EMAPTPOLBGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| CN-110878099-B | Preparation method of pyrrole [1,2, alpha ] indole alkaloid derivative | 五邑大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-110878099-A | Preparation method of pyrrole [1,2, α ] indole alkaloid derivative | 五邑大学 | 2020-03-13 | — | — | CN | disclosed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4677193-A | GONADOTROPIN-RELEASING FACTOR ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0192492-A2 | Peptides containing an aliphatic-aromatic ketone side chain | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-08-27 | — | — | EP | disclosed |