Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.70 |
| ▸ | THRB | P10828 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746934 | 0.94 | MAPT (0.68) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL2399622 | 0.90 | MAPT (0.70) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL9868985 | 0.90 | MAPT (0.56) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL12410812 | 0.88 | MAPT (0.73) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL13619848 | 0.88 | MAPT (0.73) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL14427990 | 0.87 | MAPT (0.72) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL16363773 | 0.86 | MAPT (0.74) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL23169662 | 0.86 | MAPT (0.68) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL16315811 | 0.86 | MAPT (0.70) | MAPTSMN1; SMN2THRBKDM4EALOX12 | |
| SCHEMBL9061457 | 0.85 | MAPT (0.67) | MAPTSMN1; SMN2THRBKDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171909-B1 | SPIRO-OXAZINE COMPOUNDS AND PREPARATION THEREOF AND PHOTOCHROMIC SHAPED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4784474-A | LENSES; WINDOWS | TORAY INDUSTRIES, INC. (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0171909-A1 | Spiro-oxazine compounds and preparation thereof and photochromic shaped article | TORAY INDUSTRIES, INC. (JP) | 1986-02-19 | — | — | EP | disclosed |