⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329302 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL5110341 | 0.74 | — | — | |
| SCHEMBL31435658 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL2955501 | 0.74 | — | — | |
| SCHEMBL4231810 | 0.74 | — | — | |
| SCHEMBL24017486 | 0.70 | — | — | |
| SCHEMBL11877968 | 0.70 | — | — | |
| SCHEMBL2099801 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL1472862 | 0.70 | — | — | |
| SCHEMBL11679387 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262057-B1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2020-04-15 | — | — | EP | disclosed |
| US-10428104-B2 | Substituted nucleoside derivatives useful as anticancer agents | PFIZER INC. (US) | 2019-10-01 | — | — | US | disclosed |
| EP-3262057-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Inc (US) | 2018-01-03 | — | — | EP | disclosed |
| CN-107278205-A | Substituted nucleoside derivates as anticarcinogen | 辉瑞大药厂 | 2017-10-20 | — | — | CN | disclosed |
| WO-2016135582-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2016-09-01 | — | — | WO | disclosed |
| US-20160244475-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2016-08-25 | — | — | US | disclosed |
| EP-0294686-B1 | PROCESS FOR THE PREPARATION OF DIARYLIMINOCARBONATES | BASF Aktiengesellschaft (DE) | 1992-12-09 | — | — | EP | disclosed |
| EP-0355578-A1 | Method of preparing N,N-dimethyl thiocarbamoyl chloride | CASSELLA Aktiengesellschaft (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | disclosed |