SCHEMBL97478

SCHEMBL97478

CCCCOP(=O)(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
GAA P10253 4/20 0.52
MEN1 O00255 3/20 0.52
HMGCR P04035 3/20 0.50
NR1I2 O75469 1/20 0.44
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
MAPK1 P28482 3/20 0.41
CYP3A4 P08684 3/20 0.41
MAPT P10636 3/20 0.41
CYP1A2 P05177 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
USP2 O75604 1/20 0.41
CYP2D6 P10635 1/20 0.41
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.40
GMNN O75496 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10701901 0.91 HMGCR (0.50) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL7676495 0.90 HMGCR (0.49) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL914599 0.89 HMGCR (0.50) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL9759693 0.88 KMT2A (0.47) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL12210515 0.88 GAA (0.41) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL28541822 0.86 HMGCR (0.48) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL809384 0.86 HMGCR (0.48) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL8869012 0.86 HMGCR (0.48) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL28387496 0.86 HMGCR (0.48) KMT2AGAAMEN1HMGCRNR1I2
SCHEMBL915217 0.86 HMGCR (0.48) KMT2AGAAMEN1HMGCRNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2660266-A2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2013-11-06 EP disclosed
US-8436131-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2013-05-07 US disclosed
US-8436131-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2013-05-07 US disclosed
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2013-02-07 US disclosed
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2013-02-07 US disclosed
US-8258253-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2012-09-04 US disclosed
US-8258253-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2012-09-04 US disclosed
US-8258253-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2012-09-04 US disclosed
EP-2426161-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2012-03-07 EP disclosed
EP-2426161-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2012-03-07 EP disclosed
US-8030435-B2 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION (US) 2011-10-04 US disclosed
US-8030435-B2 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION (US) 2011-10-04 US disclosed
EP-2268699-B1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2011-09-28 EP disclosed
EP-2268699-B1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2011-09-28 EP disclosed
EP-2268699-A1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2011-01-05 EP disclosed
WO-2009121796-A1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2009-10-08 WO disclosed
WO-2009121796-A1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2009-10-08 WO disclosed
US-20090253888-A1 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION 2009-10-08 US disclosed
US-20090253888-A1 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION 2009-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds PHOSPHO1, PIK3C2A, PIK3C2B KMT2A 1470/4885GAA 3072/4885MEN1 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.