Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411902 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL3762356 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL6813208 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL25078776 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL13997509 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL25078765 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL6813695 | 0.90 | PLA2G10 (0.50) | PLA2G10PLA2G2ATLR2TDP1L3MBTL1 | |
| SCHEMBL4368865 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL2411920 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 | |
| SCHEMBL6811774 | 0.90 | PLA2G10 (0.55) | PLA2G10PLA2G2ATLR2PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4921859-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4918219-A | Glycerine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-04-17 | — | — | US | disclosed |