Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28112968 | 0.94 | TSHR (0.61) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL27548214 | 0.92 | TSHR (0.65) | TSHRALDH1A1HCAR2NAAARAD52 | |
| SCHEMBL28113442 | 0.92 | TSHR (0.65) | TSHRALDH1A1HCAR2NAAARAD52 | |
| SCHEMBL27876308 | 0.88 | TSHR (0.42) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL375032 | 0.83 | TSHR (0.57) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL28347637 | 0.82 | TSHR (0.55) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL198447 | 0.82 | TSHR (0.55) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL3081526 | 0.82 | TSHR (0.55) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL3477377 | 0.82 | TSHR (0.55) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL26126122 | 0.82 | TSHR (0.55) | TSHRALDH1A1HPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106433411-B | Anti-fingerprint coating fluid and anti-fingerprint cured film | 张家港康得新光电材料有限公司 | 2019-11-08 | — | — | CN | disclosed |
| US-20170340650-A1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY | 2017-11-30 | — | — | US | disclosed |
| US-20170334946-A1 | OXOLUPENE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY | 2017-11-23 | — | — | US | disclosed |
| CN-106187287-B | A kind of scattered template for preparing microchannel haydite and the method for preparing microchannel haydite | 陕西延长石油（集团）有限责任公司 | 2017-08-08 | — | — | CN | disclosed |
| US-9527882-B2 | Triterpenoids with HIV maturation inhibitory activity | ViiV Healthcare UK (No.4) Limited (GB) | 2016-12-27 | — | — | US | disclosed |
| CN-106187287-A | A kind of dispersion template preparing microchannel haydite and the method preparing microchannel haydite | 陕西延长石油（集团）有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| WO-2016077561-A1 | OXOLUPENE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-19 | — | — | WO | disclosed |
| CN-103154042-B | Photoetching technique multipolymer and manufacture method thereof, anti-corrosion agent composition, forms the manufacture method of the substrate of pattern, the evaluation method of multipolymer, multipolymer composition analytic method | MITSUBISHI RAYON CO.,LTD. (JP) | 2015-12-16 | — | — | CN | disclosed |
| WO-2015157483-A1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY, SUBSTITUTED IN POSITION 3 BY A NON-AROMATIC RING CARRYING A HALOALKYL SUBSTITUENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-15 | — | — | WO | disclosed |
| US-20150291655-A1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2015-10-15 | — | — | US | disclosed |
| CN-103154042-A | Copolymers for lithography and method for producing same, resist composition, method for producing substrate with pattern formed thereupon, method for evaluating copolymers, and method for analyzing copolymer compositions | MITSUBISHI RAYON CO | 2013-06-12 | — | — | CN | disclosed |
| CN-101823989-B | Polymer for resist, resist composition, pattern forming method and material compound for resist polymer | MITSUBISHI RAYON CO | 2012-05-09 | — | — | CN | disclosed |
| CN-1930194-B | Resist polymer, resist composition, method for producing pattern, and raw material compound for resist polymer | MITSUBISHI RAYON CO | 2011-03-30 | — | — | CN | disclosed |
| CN-101823989-A | Resist with polymkeric substance, resist composition and method of manufacturing pattern and resist with the polymkeric substance starting compound | MITSUBISHI RAYON CO | 2010-09-08 | — | — | CN | disclosed |
| CN-1976962-B | Resist polymer, process for production thereof, resist composition, and process for production of substrates with patterns thereon | MITSUBISHI RAYON CO | 2010-06-23 | — | — | CN | disclosed |
| CN-1976962-A | Resist polymer, process for production thereof, resist composition, and process for production of substrates with patterns thereon | MITSUBISHI RAYON CO (JP) | 2007-06-06 | — | — | CN | disclosed |
| CN-1930194-A | Resist polymer, resist composition, method for producing pattern, and raw material compound for resist polymer | MITSUBISHI RAYON CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334946-A1 | OXOLUPENE DERIVATIVES | BET1, CYP51A1, PGGT1B | TSHR 4821/4885ALDH1A1 1759/4885HPGD 240/4885 |
| US-20150291655-A1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | CYP51A1, CYP8B1, LSS | TSHR 4415/4885ALDH1A1 2104/4885HPGD 2143/4885 |
| US-20170340650-A1 | TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | CYP51A1, CYP8B1, LSS | TSHR 4415/4885ALDH1A1 2104/4885HPGD 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.