SCHEMBL9748585

SCHEMBL9748585

CCCCCCCCC(=O)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.58
GNAI3 P08754 1/20 0.57
GNAO1 P09471 1/20 0.57
GNAI1 P63096 1/20 0.57
TRPV1 Q8NER1 6/20 0.51
CNR1 P21554 4/20 0.51
CNR2 P34972 4/20 0.51
NAAA Q02083 3/20 0.49
EPHX2 P34913 1/20 0.49
HTT P42858 1/20 0.48
POLB P06746 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9746901 1.00 GAA (0.58) GAAGNAI3GNAO1GNAI1TRPV1
SCHEMBL2253775 1.00 GAA (0.58) GAAGNAI3GNAO1GNAI1TRPV1
SCHEMBL10526073 1.00 GAA (0.58) GAAGNAI3GNAO1GNAI1TRPV1
SCHEMBL10723343 1.00 GAA (0.58) GAAGNAI3GNAO1GNAI1TRPV1
SCHEMBL9456922 0.94 GAA (0.65) GAAGNAI3GNAO1GNAI1HTT
SCHEMBL1647940 0.92 GAA (0.67) GAAGNAI3GNAO1GNAI1HTT
SCHEMBL28690256 0.88 GAA (0.58) GAAGNAI3GNAO1GNAI1HTT
SCHEMBL4094277 0.87 GAA (0.65) GAAHTTPOLBKMT2AMEN1
SCHEMBL9003032 0.86 GAA (0.57) GAAGNAI3GNAO1GNAI1HTT
SCHEMBL9002697 0.86 GAA (0.57) GAAGNAI3GNAO1GNAI1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272589-B1 POLYALKYL PIPERIDINE DERIVATIVES WITH ALKYLENE BRIDGES AND THEIR USE AS STABILIZERS BASF Aktiengesellschaft (DE) 1992-10-28 EP disclosed
US-4837403-A RADIATION AND HEAT RESISTANCE IMPARTED TO PLASTICS BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0272589-A2 Polyalkyl piperidine derivatives with alkylene bridges and their use as stabilizers BASF Aktiengesellschaft (DE) 1988-06-29 EP disclosed