Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916641 | 0.82 | POLB (0.53) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10514696 | 0.82 | POLB (0.52) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10920673 | 0.79 | POLB (0.51) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10920986 | 0.78 | POLB (0.54) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10752610 | 0.78 | POLB (0.47) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10922853 | 0.77 | POLB (0.51) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10918177 | 0.76 | POLB (0.50) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10920525 | 0.76 | POLB (0.64) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL8883132 | 0.76 | KMT2A (0.56) | POLBKDM4ENPC1RAB9AGAA | |
| SCHEMBL10924035 | 0.74 | POLB (0.51) | POLBNPC1RAB9AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224842-B1 | PYRAZOLESULFONAMIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND HERBICIDE CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| EP-0224842-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |