Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045306 | 0.98 | EPHX1 (0.90) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL12196188 | 0.93 | EPHX1 (1.00) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL19420655 | 0.90 | EPHX1 (0.83) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL9547553 | 0.90 | EPHX1 (0.83) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093712 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093656 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093399 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093824 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093939 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL15093650 | 0.88 | EPHX2 (0.74) | EPHX1KDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126483-A | Anticholesterol and antilipemic agents | MITSUBISHI KASEI CORPORATION (JP) | 1992-06-30 | — | — | US | disclosed |