Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747688 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9747674 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9749266 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9749262 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9747804 | 0.73 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9747800 | 0.73 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL2738965 | 0.71 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL18061255 | 0.69 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL11076575 | 0.67 | TOP2A (0.58) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL220003 | 0.67 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489733-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1990012799-A1 | ANTIBACTERIAL PYRIDO(1,2,3-DE)-1,4-BENZOXAZINONE AGENTS | THE UPJOHN COMPANY (US) | 1990-11-01 | — | — | WO | disclosed |