Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748436 | 0.85 | RARG (0.56) | RARGRARBMEN1KMT2ANPC1 | |
| SCHEMBL8457996 | 0.75 | RARG (0.54) | RARGRARBMEN1KMT2ACHRNA1 | |
| SCHEMBL8457992 | 0.75 | RARG (0.54) | RARGRARBMEN1KMT2ACHRNA1 | |
| SCHEMBL10356221 | 0.75 | RARG (0.54) | RARGRARBMEN1KMT2ACHRNA1 | |
| SCHEMBL9822540 | 0.73 | RARG (0.42) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10355941 | 0.73 | RARG (0.56) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL1422581 | 0.73 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL1782039 | 0.73 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL1782019 | 0.73 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10544523 | 0.73 | RARG (0.46) | RARGRARBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |