SCHEMBL974979

SCHEMBL974979

CCC1(C)CC2(OCC(C)(CO)CO2)C(C)C(C)(CC)N1OC(C)c1ccc(OCC2CO2)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PPARG P37231 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974233 0.94 TDP1 (0.31) TDP1TP53MAPTHPGDTSHR
SCHEMBL978443 0.94 TDP1 (0.33) TDP1TP53MAPTHPGDTSHR
SCHEMBL975029 0.92 TDP1 (0.32) TDP1TP53MAPTHPGDTSHR
SCHEMBL974702 0.92 TDP1 (0.33) TDP1TP53MAPTHPGDTSHR
SCHEMBL12922162 0.92 TDP1 (0.34) TDP1TP53MAPTHPGDTSHR
SCHEMBL975413 0.91 TDP1 (0.34) TDP1TP53MAPTHPGDTSHR
SCHEMBL975704 0.91 TDP1 (0.31) TDP1TP53MAPTHPGDTSHR
SCHEMBL7043757 0.90 TDP1 (0.33) TDP1TP53MAPTHPGDTSHR
SCHEMBL975965 0.90
SCHEMBL974645 0.90 TDP1 (0.35) TDP1TP53MAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US claimed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US claimed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP claimed
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization CIBA SPECIALTY CHEMICALS CORP. 2004-03-11 US claimed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP claimed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO claimed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
US-8544658-B2 Functionalized thin film polyamide membranes POLYMERS CRC LIMITED (AU) 2013-10-01 US disclosed
EP-2313184-B1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LTD (AU) 2012-10-10 EP disclosed
EP-2313184-B1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LTD (AU) 2012-10-10 EP disclosed
US-20110189469-A1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LIMITED (AU) 2011-08-04 US disclosed
US-20110189469-A1 FUNCTIONALIZED THIN FILM POLYAMIDE MEMBRANES POLYMERS CRC LIMITED (AU) 2011-08-04 US disclosed
US-6967228-B2 Stable free radical polymers FIRESTONE POLYMERS, LLC (US) 2005-11-22 US disclosed
US-20040220344-A1 Stable free radical polymers FIRESTONE POLYMERS, LLC. 2004-11-04 US disclosed
US-20040220345-A1 Stable free radical polymers FIRESTONE POLYMERS, LLC 2004-11-04 US disclosed
EP-1473312-A2 Stable free radical polymers Firestone Polymers, LLC (US) 2004-11-03 EP disclosed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP disclosed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP disclosed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PTGER4, ALKBH3, PIGO TDP1 3387/4885TP53 4722/4885MAPT 3644/4885
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PAOX, ALKBH3, PTGER4 TDP1 2766/4885TP53 4311/4885MAPT 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.