Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750140 | 0.78 | TDP1 (0.33) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL9625997 | 0.76 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2185889 | 0.74 | HDAC8 (0.50) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL3932080 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL9212693 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL912228 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL9064629 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL338461 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL28988244 | 0.71 | TSHR (0.94) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 | |
| Water SCHEMBL8617710 | 0.69 | TSHR (0.89) | TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081249-A | From gaseous fluorine and solution of pyridinesulfonate | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-01-14 | — | — | US | disclosed |