Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830299 | 0.80 | ESR1 (0.56) | ESR1ESR2ARVDR | |
| SCHEMBL416522 | 0.78 | ESR1 (0.52) | ESR1ESR2ARESRRGALDH1A1 | |
| SCHEMBL5034647 | 0.75 | ESR1 (0.62) | ESR1ESR2ARALDH1A1HPGD | |
| SCHEMBL29471727 | 0.73 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29465776 | 0.73 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL217305 | 0.73 | ESR1 (0.80) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL171132 | 0.73 | ESR1 (0.74) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29350788 | 0.73 | ESR1 (1.00) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL31621104 | 0.73 | ESR1 (0.74) | ESR1ESR2ARTDP1TP53 | |
| SCHEMBL29360146 | 0.73 | ESR1 (1.00) | ESR1ESR2ARTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102693-A | Calendering intermediate layer to smooth surface, coating onto support and forming a thermosensitive coloring layer | RICOH COMPANY, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-4975408-A | INTERMEDIATE INSULATING LAYER HAVING SURFACE SMOOTHNESS GIVING IMPROVED COLORING SENSITIVITY; FOAMED LAYER HAVING MINUTE VOIDS | RICOH COMPANY, LTD. (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4895828-A | INTERMEDIATE EXPANDED PLASTIC FILLER LAYER AND ELECTROCONDUCTIVE MATERIAL | RICOH COMPANY, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |