⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804 | 0.75 | — | — | |
| SCHEMBL8402436 | 0.75 | — | — | |
| SCHEMBL9750466 | 0.71 | — | — | |
| SCHEMBL3675358 | 0.70 | GSK3A (0.47) | — | |
| SCHEMBL3675360 | 0.70 | GSK3A (0.47) | — | |
| SCHEMBL5162547 | 0.62 | — | — | |
| SCHEMBL5160405 | 0.62 | — | — | |
| SCHEMBL7193277 | 0.62 | — | — | |
| 5,6-Dihydro-2(1H)-Pyridinone SCHEMBL49488 | 0.62 | — | — | |
| SCHEMBL319178 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212569-B1 | THIATION PROCESS | ETHYL CORPORATION (US) | 1991-05-22 | — | — | EP | claimed |
| US-4935514-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| US-4935513-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| US-4935510-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | claimed |
| US-4663452-A | Thiation process | ETHYL CORPORATION (US) | 1987-05-05 | — | — | US | claimed |
| EP-0212569-A2 | Thiation process | ETHYL CORPORATION (US) | 1987-03-04 | — | — | EP | claimed |
| EP-0212569-B1 | THIATION PROCESS | ETHYL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0107930-B1 | FUSED AROMATIC OXAZEPINONES AND SULPHUR ANALOGUES THEREOF AND THEIR PREPARATION AND USE IN COUNTERACTING HISTAMINE | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4935514-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4935513-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4935510-A | Thiation process | ETHYL CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4663452-A | Thiation process | ETHYL CORPORATION (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0212569-A2 | Thiation process | ETHYL CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4604388-A | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof in a method of counteracting histamine | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0107930-A2 | Fused aromatic oxazepinones and sulphur analogues thereof and their preparation and use in counteracting histamine | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1984-05-09 | — | — | EP | disclosed |