SCHEMBL9750778

SCHEMBL9750778

CCNc1cc(O)c(NCC)cc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
RECQL P46063 1/20 0.50
IDO1 P14902 3/20 0.48
PGK1 P00558 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
GFER P55789 1/20 0.38
PLEC Q15149 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
G6PD P11413 1/20 0.37
SHMT2 P34897 1/20 0.34
HCAR3 P49019 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685122 0.95 TSHR (0.47) CYP3A4TSHRRECQLIDO1PGK1
SCHEMBL26429542 0.89 CYP3A4 (0.52) CYP3A4TSHRRECQLIDO1PGK1
SCHEMBL26429718 0.83 HMGCR (0.47) CYP3A4TSHRRECQLIDO1PGK1
SCHEMBL23714520 0.80 CYP3A4 (0.59) CYP3A4TSHRRECQLIDO1PGK1
SCHEMBL28278780 0.79 CYP3A4 (0.62) CYP3A4TSHRRECQLIDO1KDM4E
SCHEMBL1368372 0.77 IDO1 (0.59) CYP3A4TSHRRECQLIDO1KDM4E
SCHEMBL30086871 0.77 CYP3A4 (0.50) CYP3A4TSHRRECQLIDO1GAA
SCHEMBL1259060 0.77 CYP3A4 (0.50) CYP3A4TSHRRECQLIDO1GAA
SCHEMBL11211267 0.77 CYP3A4 (0.50) CYP3A4TSHRRECQLIDO1KDM4E
SCHEMBL27534388 0.75 IDO1 (0.47) CYP3A4TSHRRECQLIDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0246112-B1 PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1991-06-12 EP disclosed
EP-0324847-A4 PREPARATION OF BIS (AMINE-CONTAINING) BENZENEDIOLS 1991-03-20 EP disclosed
EP-0324847-A1 PREPARATION OF BIS (AMINE-CONTAINING) BENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1989-07-26 EP disclosed
US-4806688-A Preparation of diamino- and dialkylaminobenzenediols THE DOW CHEMICAL COMPANY (US) 1989-02-21 US disclosed
WO-1989000556-A1 PREPARATION OF BIS (AMINE-CONTAINING) BENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1989-01-26 WO disclosed
EP-0246112-A1 Preparation of diamino- and dialkylaminobenzenediols THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
WO-1987006930-A1 PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS THE DOW CHEMICAL COMPANY (US) 1987-11-19 WO disclosed