Phenol

Phenol

SCHEMBL9750792

C=C.N.N.Oc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.79
CA2 P00918 4/20 0.79
CA14 Q9ULX7 4/20 0.79
CA9 Q16790 3/20 0.79
CA3 P07451 3/20 0.79
CA4 P22748 3/20 0.79
TDP1 Q9NUW8 3/20 0.79
CA1 P00915 2/20 0.79
GLA P06280 1/20 0.79
MMP3 P08254 1/20 0.53
BCL2L1 Q07817 1/20 0.53
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 4/20 0.47
NPC1 O15118 3/20 0.47
LMNA P02545 3/20 0.47
CA5A P35218 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL29209556 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL28489535 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL27547373 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL644783 0.96 CA12 (0.85) CA12CA2CA14CA9CA3
Phenol SCHEMBL481476 0.96
Phenol SCHEMBL28021424 0.93 CA12 (0.79) CA12CA2CA14CA9CA3
Phenol SCHEMBL27964958 0.93 CA12 (0.79) CA12CA2CA14CA9CA3
Phenol SCHEMBL28233422 0.93 CA12 (0.79) CA12CA2CA14CA9CA3
Phenol SCHEMBL27375372 0.93 CA12 (0.79) CA12CA2CA14CA9CA3
Phenol SCHEMBL28189313 0.93 CA12 (0.79) CA12CA2CA14CA9CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321548-A4 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES 1991-01-30 EP disclosed
US-4904582-A Novel amphiphilic nucleic acid conjugates SYNTHETIC GENETICS (US) 1990-02-27 US disclosed
WO-1989005853-A1 NUCLEIC ACID CHELATE CONJUGATE AS THERAPEUTIC AND DIAGNOSTIC AGENTS SYNTHETIC GENETICS (US) 1989-06-29 WO disclosed
EP-0321548-A1 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES SYNTHETIC GENETICS (US) 1989-06-28 EP disclosed
WO-1988009810-A1 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES SYNTHETIC GENETICS (US) 1988-12-15 WO disclosed