⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19557815 | 0.77 | — | — | |
| SCHEMBL5691862 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL2359587 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL1680583 | 0.73 | — | — | |
| SCHEMBL1680582 | 0.73 | — | — | |
| SCHEMBL24141565 | 0.72 | — | — | |
| SCHEMBL13328647 | 0.71 | — | — | |
| SCHEMBL28148278 | 0.71 | — | — | |
| SCHEMBL37295 | 0.69 | — | — | |
| SCHEMBL37294 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321556-A4 | USE OF C-5 MONO-SUBSTITUTED BARBITURATES TO TREAT DISORDERS OF URIC ACID METABOLISM | — | 1991-06-12 | — | — | EP | claimed |
| EP-0321556-A1 | USE OF C-5 MONO-SUBSTITUTED BARBITURATES TO TREAT DISORDERS OF URIC ACID METABOLISM | Memorial Hospital for Cancer and Allied Diseases (US) | 1989-06-28 | — | — | EP | claimed |
| WO-1988010114-A1 | USE OF C-5 MONO-SUBSTITUTED BARBITURATES TO TREAT DISORDERS OF URIC ACID METABOLISM | MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (US) | 1988-12-29 | — | — | WO | claimed |