Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.78 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.78 |
| ▸ | CA12 | O43570 | 6/20 | 0.68 |
| ▸ | CA1 | P00915 | 6/20 | 0.68 |
| ▸ | CA2 | P00918 | 6/20 | 0.68 |
| ▸ | CA7 | P43166 | 6/20 | 0.68 |
| ▸ | CA9 | Q16790 | 6/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12552740 | 0.90 | CYP3A4 (0.74) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL11207308 | 0.88 | NR1H2 (1.00) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL20378742 | 0.86 | NR1H2 (0.75) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL12552819 | 0.84 | NR1H2 (0.57) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL11315535 | 0.83 | NR1H2 (0.71) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL5788019 | 0.81 | CA12 (1.00) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL571273 | 0.81 | CYP3A4 (0.61) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL31643756 | 0.80 | NR1H2 (0.67) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL28519674 | 0.80 | NR1H2 (0.66) | NR1H2NR1H3CA12CA1CA2 | |
| SCHEMBL7601281 | 0.80 | NR1H2 (0.51) | NR1H2NR1H3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401215-A4 | HYDROPHILIC CARBOXY POLYURETHANES | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0401215-A1 | HYDROPHILIC CARBOXY POLYURETHANES | TYNDALE PLAINS-HUNTER, LTD. (US) | 1990-12-12 | — | — | EP | disclosed |
| WO-1989007619-A1 | HYDROPHILIC CARBOXY POLYURETHANES | TYNDALE PLAINS-HUNTER, LTD. (US) | 1989-08-24 | — | — | WO | disclosed |
| US-4743673-A | MEDICAL EQUIPMENT, DRUG DELIVERY, ANTIFRICTION | TYNDALE PLAINS-HUNTER, LTD. (US) | 1988-05-10 | — | — | US | disclosed |