Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.58 |
| ▸ | PCNA | P12004 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168147 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL1667022 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL11676390 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL11370023 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL11520038 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL60228 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL10978818 | 0.87 | SLC7A5 (0.73) | SLC7A5PCNAPTPN1ITGB3ITGA2B | |
| SCHEMBL4629444 | 0.86 | SLC7A5 (0.56) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| SCHEMBL9937712 | 0.86 | SLC7A5 (0.56) | SLC7A5PTPN1ITGB3ITGA2BPTGS1 | |
| SCHEMBL15555538 | 0.84 | SLC7A5 (0.48) | SLC7A5PCNAPTPN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411018-A4 | DETECTION, QUANTITATION AND CLASSIFICATION OF RAS PROTEINS IN BODY FLUIDS AND TISSUES | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0411018-A1 | DETECTION, QUANTITATION AND CLASSIFICATION OF RAS PROTEINS IN BODY FLUIDS AND TISSUES. | DU PONT (US) | 1991-02-06 | — | — | EP | disclosed |
| WO-1989010565-A1 | DETECTION, QUANTITATION AND CLASSIFICATION OF RAS PROTEINS IN BODY FLUIDS AND TISSUES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-02 | — | — | WO | disclosed |