Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | PPOX | P50336 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751497 | 0.93 | TDP1 (0.58) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10668736 | 0.89 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10553434 | 0.88 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10667110 | 0.86 | TDP1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9751309 | 0.84 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10748703 | 0.83 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10806230 | 0.83 | KMT2A (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9751619 | 0.82 | TDP1 (0.46) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10359539 | 0.82 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10673745 | 0.82 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992089-A | Pre- and postemergence | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0228788-B1 | HERBICIDAL DERIVATIVES OF SUBSTITUTED BENZOYL-HYDRAZINIUM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0228788-A1 | Herbicidal derivatives of substituted benzoyl-hydrazinium compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |