Diphenylether

Diphenylether

SCHEMBL9751558

Cc1ccccc1-c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.52
TSHR P16473 2/20 0.52
GSTP1 P09211 1/20 0.48
BTK Q06187 1/20 0.46
ENPP3 O14638 1/20 0.45
ENPP1 P22413 1/20 0.45
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
ESR2 Q92731 1/20 0.44
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706107 0.86 ESR2 (0.54) TSHRENPP3ENPP1NPC1ALDH1A1
SCHEMBL616 0.86 ESR2 (0.54) TSHRENPP3ENPP1NPC1ALDH1A1
Bromide SCHEMBL1925857 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
SCHEMBL29222873 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Hydrochloric Acid SCHEMBL28832617 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Biphenyl SCHEMBL4733975 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Ammonia Solution, Strong SCHEMBL19032131 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Biphenyl SCHEMBL4603527 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Water SCHEMBL8948779 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1
Iodide SCHEMBL31053161 0.84 ESR2 (0.52) TSHRENPP3ENPP1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400066-A4 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME 1991-03-20 EP disclosed
EP-0400066-A1 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1990-12-05 EP disclosed
WO-1989007634-A1 HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1989-08-24 WO disclosed