SCHEMBL9751666

SCHEMBL9751666

C=CC1(C(=O)O)CCCC1C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
NR1H3 Q13133 1/20 0.31
PTPN1 P18031 1/20 0.31
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081567 0.77
SCHEMBL23855001 0.72 GRM2 (0.32) CYP1A2CYP2C19
SCHEMBL28859979 0.69 CYP1A2 (0.36) CYP1A2CYP2C19
SCHEMBL4024099 0.69 CYP1A2 (0.34) CYP1A2
SCHEMBL988593 0.69 CYP1A2 (0.38) CYP1A2CYP2C19
SCHEMBL2277287 0.67 FFAR3 (0.39) CYP1A2PTPN1CYP2C19
SCHEMBL2277283 0.67 FFAR3 (0.39) CYP1A2PTPN1CYP2C19
SCHEMBL7439240 0.67 CYP1A2 (0.37) CYP1A2CYP2C19
SCHEMBL2277288 0.67 FFAR3 (0.39) CYP1A2PTPN1CYP2C19
SCHEMBL17821216 0.66 CYP1A2 (0.32) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398941-A4 DRY POWDER DIAGNOSTIC REAGENT AND APPLICATIONS THEREOF 1991-04-10 EP disclosed
EP-0398941-A1 DRY POWDER DIAGNOSTIC REAGENT AND APPLICATIONS THEREOF BOEHRINGER MANNHEIM CORPORATION (US) 1990-11-28 EP disclosed
WO-1989006284-A1 DRY POWDER DIAGNOSTIC REAGENT AND APPLICATIONS THEREOF BOEHRINGER MANNHEIM CORPORATION (US) 1989-07-13 WO disclosed