Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660901 | 0.75 | MAPT (0.39) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL5837737 | 0.75 | BRD4 (0.42) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL6773172 | 0.75 | BRD4 (0.42) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL3808275 | 0.72 | GAA (0.35) | MAPTGAAALDH1A1CYP1A2POLB | |
| SCHEMBL29192390 | 0.72 | BRD4 (0.38) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL1144876 | 0.71 | AHR (0.37) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL25987161 | 0.71 | BRD4 (0.37) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL27333155 | 0.69 | BRD4 (0.36) | MAPTGAAMEN1KMT2ABRD4 | |
| SCHEMBL28560295 | 0.69 | GAA (0.39) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21143033 | 0.68 | MAPT (0.38) | MAPTGAAMEN1KMT2AAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013190212-A1 | METHOD FOR PRODUCING CHIRAL PEPTIDES | DIVERCHIM (FR) | 2013-12-27 | — | — | WO | disclosed |
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990006937-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |