Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oberadilol SCHEMBL8813275 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| Oberadilol SCHEMBL29711553 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| Oberadilol SCHEMBL9656824 | 0.95 | CASR (0.42) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| Oberadilol SCHEMBL9656812 | 0.95 | CASR (0.42) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9657696 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9657593 | 0.91 | PDE3B (0.45) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| Oberadilol SCHEMBL29787351 | 0.91 | PDE3B (0.42) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9654276 | 0.90 | PDE3B (0.45) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9656783 | 0.89 | PDE3B (0.44) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 | |
| SCHEMBL9656819 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3005465-A | — | — | None | — | — | JP | disclosed |
| JP-H035465-A | OPTICALLY ACTIVE PYRIDAZINONE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD | 1991-01-11 | — | — | JP | disclosed |