Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20358289 | 0.93 | RARB (0.54) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL10481180 | 0.92 | CYP3A4 (0.52) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330690 | 0.92 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330971 | 0.92 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL10481197 | 0.92 | CYP3A4 (0.52) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL10355270 | 0.92 | CYP3A4 (0.52) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9330957 | 0.92 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9333696 | 0.92 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9333683 | 0.92 | RARB (0.48) | RARBNR5A1CYP3A4CYP2D6SLC2A1 | |
| SCHEMBL9752271 | 0.92 | CYP3A4 (0.52) | RARBNR5A1CYP3A4CYP2D6SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3176444-A | — | — | None | — | — | JP | disclosed |
| JP-H03176444-A | BIPHENYL DERIVATIVE | DAINIPPON INK & CHEM INC | 1991-07-31 | — | — | JP | disclosed |