Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752290 | 1.00 | GRM4 (0.49) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL9550324 | 0.79 | — | — | |
| SCHEMBL2674256 | 0.77 | GRM4 (0.52) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL2593887 | 0.77 | GRM4 (0.52) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL15772906 | 0.76 | GRM4 (0.54) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL9631621 | 0.76 | GRM4 (0.45) | GRM4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3505995 | 0.75 | GRM4 (0.53) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL19974222 | 0.72 | GRM4 (0.50) | GRM4GAAPOLBALDH1A1TDP1 | |
| SCHEMBL9550312 | 0.71 | — | — | |
| SCHEMBL8830406 | 0.70 | GRM4 (0.49) | GRM4GAAPOLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |