Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752373 | 1.00 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9752515 | 0.96 | HSD17B10 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28657451 | 0.89 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022485 | 0.84 | CHRM2 (0.67) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022489 | 0.84 | CHRM2 (0.67) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10082580 | 0.82 | HPGD (0.50) | — | |
| SCHEMBL15317053 | 0.82 | HPGD (0.50) | — | |
| SCHEMBL525478 | 0.82 | HPGD (0.50) | — | |
| SCHEMBL9752320 | 0.81 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9752355 | 0.81 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |