Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD1 | P49961 | 3/20 | 0.74 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752399 | 1.00 | ENTPD1 (0.74) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL12932272 | 0.99 | ENTPD1 (0.76) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL1062562 | 0.99 | ENTPD1 (0.76) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL30292631 | 0.99 | ENTPD1 (0.76) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL9702967 | 0.92 | SIRT2 (0.72) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL9702452 | 0.92 | SIRT2 (0.72) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL20277574 | 0.92 | SIRT2 (0.72) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL20277592 | 0.92 | SIRT2 (0.72) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL29398104 | 0.91 | ENTPD1 (0.74) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL636535 | 0.90 | ENTPD1 (0.75) | ENTPD1TRPM2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000346-A1 | POLYNUCLEOTIDE PHOSPHORYLASE IMMOBILIZED ON TRIS(HYDROXYMETHYL)METHYLACRYLAMIDE POLYMER BEADS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0346865-A2 | Polynucleotide phosphorylase immobilized on epoxy-activated beads | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-12-20 | — | — | EP | disclosed |