Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9752451 | 1.00 | BLM (0.47) | BLMCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9752524 | 0.95 | CHRM2 (0.50) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9752361 | 0.95 | CHRM2 (0.50) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9752294 | 0.91 | CHRM2 (0.53) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9752331 | 0.91 | CHRM2 (0.53) | CHRM2CHRM5CHRM1CHRM3CYP2D6 | |
| SCHEMBL9752308 | 0.77 | CHRM2 (0.47) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL9752337 | 0.77 | CHRM2 (0.47) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| Oxalic Acid SCHEMBL9752396 | 0.77 | BLM (0.41) | BLMCHRM2CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL9752673 | 0.75 | BLM (0.46) | BLMCHRM2CHRM5CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL9752330 | 0.75 | BLM (0.46) | BLMCHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |