SCHEMBL9752687

SCHEMBL9752687

COc1cc(O)c(C(C)=O)c(O)c1C(C)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.65
USP2 O75604 1/20 0.65
MAPK1 P28482 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
HTT P42858 1/20 0.55
LMNA P02545 1/20 0.52
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
HPGD P15428 1/20 0.48
FASN P49327 1/20 0.46
PTGS2 P35354 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ABL1 P00519 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
RECQL P46063 1/20 0.44
RIN1 Q13671 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
SYNJ2 O15056 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9752762 0.90 CYP3A4 (0.78) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL28132534 0.85 CYP3A4 (0.77) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL31055010 0.85 CYP3A4 (0.77) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL24106158 0.83 CYP3A4 (0.59) CYP3A4USP2MAPK1SMN1; SMN2HTT
Methoxymethane SCHEMBL9752688 0.83 CYP3A4 (0.56) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL10339706 0.81 CYP3A4 (0.56) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL1258932 0.80 CYP3A4 (0.64) CYP3A4USP2MAPK1SMN1; SMN2KMT2A
SCHEMBL1937218 0.80 CYP3A4 (0.76) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL29757572 0.80 CYP3A4 (0.76) CYP3A4USP2MAPK1SMN1; SMN2HTT
SCHEMBL12649817 0.79 CYP3A4 (0.49) CYP3A4USP2MAPK1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991009595-A1 ANTI-VIRAL COMPOSITIONS SMITHKLINE BEECHAM CORPORATION (US) 1991-07-11 WO disclosed