Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608589 | 0.91 | CYP3A4 (0.56) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL10498389 | 0.86 | CYP3A4 (0.55) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL679428 | 0.84 | CYP3A4 (0.68) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL9752762 | 0.82 | CYP3A4 (0.78) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL20867726 | 0.82 | CYP3A4 (0.47) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL10497869 | 0.80 | CA9 (0.51) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL27842593 | 0.79 | CYP3A4 (0.53) | CYP3A4MAPK1USP2SMN1; SMN2LMNA | |
| SCHEMBL5339165 | 0.79 | POLB (0.47) | CYP3A4MAPK1USP2SMN1; SMN2KMT2A | |
| SCHEMBL6895045 | 0.78 | TNFSF11 (0.55) | CYP3A4MAPK1USP2SMN1; SMN2HTT | |
| SCHEMBL24488868 | 0.78 | GAA (0.44) | CYP3A4MAPK1USP2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |