SCHEMBL9753030

SCHEMBL9753030

Cc1cc(N)c(S(=O)(=O)O)cc1Cl.Cc1cc(S(=O)(=O)O)c(N)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.55
CA12 O43570 7/20 0.45
CA1 P00915 7/20 0.45
CA2 P00918 7/20 0.45
CA9 Q16790 7/20 0.45
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 3/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72936 0.96 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL29489238 0.96 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL315975 0.96 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL29350461 0.96 CD44 (0.54) CD44CA12CA1CA2CA9
SCHEMBL9706822 0.95 CD44 (0.52) CD44CA12CA1CA2CA9
SCHEMBL30586216 0.95 CD44 (0.52) CD44CA12CA1CA2CA9
SCHEMBL27990790 0.95 CD44 (0.52) CD44CA12CA1CA2CA9
SCHEMBL1733790 0.85 CA1 (0.52) CD44CA12CA1CA2CA9
SCHEMBL30557456 0.85 CA1 (0.52) CD44CA12CA1CA2CA9
SCHEMBL6938187 0.85 CYP3A4 (0.44) CD44ALDH1A1TSHRCYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO disclosed
US-4906739-A Fibre-reactive azo dyes containing a monofluororotriazine group CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed