Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13709403 | 0.89 | GAA (0.48) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL563195 | 0.88 | GAA (0.56) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL13726604 | 0.86 | GAA (0.45) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL13335576 | 0.85 | GAA (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL2943131 | 0.84 | CYP1A2 (0.59) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL4476235 | 0.84 | GAA (0.61) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL6303688 | 0.84 | GAA (0.61) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL7892333 | 0.83 | GAA (0.50) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL1223746 | 0.82 | GAA (0.58) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL1549737 | 0.82 | GAA (0.58) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |