SCHEMBL9753254

SCHEMBL9753254

CCOC(=O)C(C#N)=Cc1ccccc1OCC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.74
KDM4E B2RXH2 2/20 0.74
MEN1 O00255 2/20 0.74
CYP1A2 P05177 1/20 0.74
CYP2C9 P11712 1/20 0.74
MAPT P10636 8/20 0.59
ALDH1A1 P00352 7/20 0.59
MIF P14174 1/20 0.59
ATM Q13315 1/20 0.58
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
STAT1 P42224 1/20 0.57
POLB P06746 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
NPSR1 Q6W5P4 2/20 0.55
LMNA P02545 4/20 0.55
PKM P14618 2/20 0.53
PLIN1 O60240 1/20 0.53
PLIN5 Q00G26 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9753251 1.00 KMT2A (0.74) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL21457627 0.91 KDM4E (0.69) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL21457624 0.91 KDM4E (0.69) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL21457613 0.89 KMT2A (0.74) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL4661342 0.89 MAPT (0.68) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL21457611 0.89 KMT2A (0.74) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL4661347 0.89 MAPT (0.68) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL11669949 0.89 MAPT (0.68) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL3067150 0.89 KMT2A (0.59) KMT2AKDM4EMEN1CYP1A2CYP2C9
SCHEMBL21457483 0.89 KDM4E (0.66) KMT2AKDM4EMEN1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3181919-A None JP disclosed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
JP-H03181919-A ORGANIC NONLINEAR OPTICAL MATERIAL SEKISUI CHEM CO LTD 1991-08-07 JP disclosed