Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753326 | 1.00 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9753589 | 0.91 | HMGCR (0.41) | HMGCR | |
| SCHEMBL9753585 | 0.91 | HMGCR (0.41) | HMGCR | |
| SCHEMBL9753411 | 0.89 | HMGCR (0.53) | HMGCR | |
| SCHEMBL9753234 | 0.86 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9753235 | 0.86 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9753286 | 0.84 | HMGCR (0.41) | HMGCR | |
| SCHEMBL9753292 | 0.84 | HMGCR (0.41) | HMGCR | |
| SCHEMBL9753311 | 0.83 | HMGCR (0.42) | HMGCR | |
| SCHEMBL9753308 | 0.83 | HMGCR (0.42) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |