Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753078 | 1.00 | HMGCR (0.40) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753079 | 1.00 | HMGCR (0.40) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753380 | 1.00 | HMGCR (0.40) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753725 | 0.93 | HMGCR (0.43) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9752972 | 0.93 | HMGCR (0.43) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753729 | 0.93 | HMGCR (0.43) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9752974 | 0.93 | HMGCR (0.43) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753700 | 0.91 | HMGCR (0.41) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753706 | 0.91 | HMGCR (0.41) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL9753469 | 0.90 | HMGCR (0.40) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |