Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cp-99994 SCHEMBL29375350 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL3951618 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL1282327 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL3951615 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL6827944 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL14513344 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL9295413 | 0.79 | TACR1 (1.00) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL8871751 | 0.78 | TACR1 (0.98) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL29406855 | 0.78 | TACR1 (0.98) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Cp-99994 SCHEMBL2139670 | 0.78 | TACR1 (0.98) | TACR1CYP2D6KCNH2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009844-A1 | SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |