⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043322 | 0.67 | — | — | |
| SCHEMBL2042932 | 0.65 | — | — | |
| SCHEMBL12153731 | 0.61 | — | — | |
| SCHEMBL2044255 | 0.60 | — | — | |
| SCHEMBL3117258 | 0.57 | — | — | |
| SCHEMBL5899081 | 0.56 | — | — | |
| SCHEMBL4645948 | 0.54 | — | — | |
| SCHEMBL245729 | 0.51 | — | — | |
| SCHEMBL7009257 | 0.48 | — | — | |
| SCHEMBL1351735 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018902-A1 | SUBSTITUTED 1-H-PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDES | SCHERING CORPORATION (US) | 1991-12-12 | — | — | WO | claimed |
| EP-0150984-B1 | 6-(SUBSTITUTED) METHYLENEPENICILLANIC AND 6-(SUBSTITUTED) HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1991-09-11 | — | — | EP | claimed |
| US-5023265-A | Antiinflammatory agent; inhibits both 5-lipoxygenase and cyclooxygenase; rheumatoid arthritis, bursitis, tendonitis, gout; side effect reduction | SCHERING CORPORATION (US) | 1991-06-11 | — | — | US | claimed |
| CN-1046905-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penicillin alkanoic acid class and derivative thereof | PFIZER (US) | 1990-11-14 | — | — | CN | claimed |
| CN-1045787-A | The method for making of 6-(replacement) methylene radical penam acids, 6-(replacement) methylol penam acids and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| CN-1045789-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penam acids and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| CN-1045788-A | 6-(replacement) methylene radical penam acids; The method for making of 6-(replacement) methylol penicillin alkanoic acid class and derivative thereof | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| CN-85101572-A | Process for producing 6- (substituted) methylenepenicillanic acids, 6- (substituted) hydroxymethylpenicillanic acids and derivatives thereof | — | 1986-10-29 | — | — | CN | claimed |
| EP-0150984-A2 | 6-(Substituted) methylenepenicillanic and 6-(substituted) hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1985-08-07 | — | — | EP | claimed |
| WO-1991018902-A1 | SUBSTITUTED 1-H-PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDES | SCHERING CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| US-5023265-A | Antiinflammatory agent; inhibits both 5-lipoxygenase and cyclooxygenase; rheumatoid arthritis, bursitis, tendonitis, gout; side effect reduction | SCHERING CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |