Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753677 | 0.90 | GAA (0.37) | GAAPTGS1PTGS2 | |
| SCHEMBL9753339 | 0.82 | — | — | |
| SCHEMBL9753691 | 0.79 | GAA (0.37) | GAAPTGS1PTGS2 | |
| SCHEMBL9753658 | 0.79 | PTGS1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL8606427 | 0.79 | GAA (0.41) | GAAPTGS1PTGS2 | |
| SCHEMBL8608469 | 0.75 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL8607694 | 0.75 | PTGS1 (0.39) | GAAPTGS1PTGS2 | |
| SCHEMBL8604762 | 0.74 | RXFP1 (0.32) | — | |
| SCHEMBL9753401 | 0.74 | PTGS1 (0.40) | GAAPTGS1PTGS2 | |
| SCHEMBL8606683 | 0.73 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | claimed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | claimed |
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | disclosed |
| WO-1991008211-A1 | IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY | G.D. SEARLE & CO. (US) | 1991-06-13 | — | — | WO | disclosed |