Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909801 | 1.00 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1694528 | 1.00 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6314315 | 0.86 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL11763385 | 0.84 | EPHX2 (0.54) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL24105901 | 0.81 | EPHX2 (0.58) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL11358783 | 0.81 | EPHX2 (0.54) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1071969 | 0.80 | MEN1 (0.59) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL22345049 | 0.80 | MEN1 (0.59) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL3299879 | 0.80 | EPHX2 (0.61) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL23898650 | 0.80 | MEN1 (0.59) | EPHX2MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018890-A1 | BICYCLIC CHIRAL COMPOUNDS | THE BRITISH PETROLEUM COMPANY PLC (GB) | 1991-12-12 | — | — | WO | disclosed |