SCHEMBL9754231

SCHEMBL9754231

CCOC1=CC(=O)OC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.43
CDC25B P30305 1/20 0.43
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
PABPC1 P11940 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 1/20 0.33
NQO1 P15559 1/20 0.32
CYP3A4 P08684 1/20 0.32
ELANE P08246 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CYP1A2 P05177 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15672207 0.83 CYP2A6 (0.36) PTPRCCDC25BKDM4EMEN1MAPT
SCHEMBL8598340 0.75 PTPN1 (0.38) ALDH1A1CA12CA1CA9
SCHEMBL15672211 0.75 PTPN1 (0.31)
SCHEMBL2961774 0.75
SCHEMBL6566935 0.74
SCHEMBL8905991 0.74 PTPRC (0.47) PTPRCKDM4EMEN1MAPTKMT2A
SCHEMBL15672436 0.74 MAPT (0.33) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL15672222 0.74 APP (0.33) KDM4EALDH1A1
SCHEMBL15672208 0.74 APP (0.33) KDM4EALDH1A1
SCHEMBL9794644 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991016189-A1 POLYMER GRAFTING PROCESS, APPARATUS AND PRODUCTS OBTAINED THEREWITH EXXON CHEMICAL PATENTS INC. (US) 1991-10-31 WO claimed
US-9786952-B2 Lithium secondary cell including an electrolytic solution including cyclic acid anhydrides NEC CORPORATION (JP) 2017-10-10 US disclosed
US-9701667-B2 Coumarin-based fluorogenic agents and uses thereof for specific protein labelling UNIVERSITY OF OTTAWA (CA) 2017-07-11 US disclosed
US-9701667-B2 Coumarin-based fluorogenic agents and uses thereof for specific protein labelling UNIVERSITY OF OTTAWA (CA) 2017-07-11 US disclosed
US-20150316557-A1 COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING UNIVERSITY OF OTTAWA (CA) 2015-11-05 US disclosed
US-20150316557-A1 COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING UNIVERSITY OF OTTAWA (CA) 2015-11-05 US disclosed
US-20140120415-A1 LITHIUM SECONDARY CELL NEC CORPORATION (JP) 2014-05-01 US disclosed
US-7161022-B2 Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative FUJIFILM FINECHEMICALS CO., LTD. (JP) 2007-01-09 US disclosed
US-7161022-B2 Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative FUJIFILM FINECHEMICALS CO., LTD. (JP) 2007-01-09 US disclosed
WO-1991016189-A1 POLYMER GRAFTING PROCESS, APPARATUS AND PRODUCTS OBTAINED THEREWITH EXXON CHEMICAL PATENTS INC. (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150316557-A1 COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING PFDN1, PFDN6, CDC73 PTPRC 3282/4885CDC25B 2677/4885KDM4E 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.