Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330609 | 0.80 | MEN1 (0.68) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL9131036 | 0.79 | TBXA2R (0.82) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL9754552 | 0.78 | MEN1 (0.84) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL1660980 | 0.77 | POLB (0.41) | MEN1KMT2AALDH1A1TAAR1 | |
| SCHEMBL10391959 | 0.77 | MEN1 (0.60) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL10391960 | 0.76 | MEN1 (0.63) | MEN1KMT2ATBXA2RPRMT1TP53 | |
| SCHEMBL1287281 | 0.74 | PRMT1 (0.83) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL9329269 | 0.74 | TBXA2R (0.70) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL9128731 | 0.73 | TBXA2R (0.72) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL9485346 | 0.73 | TBXA2R (0.72) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013868-A1 | PHENYLTHIOALKYLCARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-19 | — | — | WO | disclosed |