SCHEMBL9754645

SCHEMBL9754645

CC(CO)(CO)NCc1cccc2c1oc1cc3ccoc3cc12

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.35
CD274 Q9NZQ7 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CTNNB1 P35222 1/20 0.31
WNT3A P56704 1/20 0.31
KDM4E B2RXH2 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9843630 0.99 SLC2A1 (0.35) SLC2A1CD274HDAC8CTNNB1WNT3A
SCHEMBL9754480 0.82 CTNNB1 (0.37) CTNNB1WNT3AKDM4EPTPN1
SCHEMBL9754594 0.78 HTR1B (0.35) CD274CTNNB1WNT3APTPN1
Hydrochloric Acid SCHEMBL9754578 0.77 HTR1B (0.34) CD274CTNNB1WNT3APTPN1
SCHEMBL9779167 0.74 SLC2A1 (0.41) SLC2A1CD274KDM4E
SCHEMBL9754562 0.73 SLC2A1 (0.34) SLC2A1CD274
Hydrochloric Acid SCHEMBL9754511 0.72 SLC2A1 (0.34) SLC2A1CD274
SCHEMBL9779113 0.70 SLC2A1 (0.48) SLC2A1KDM4E
SCHEMBL9536377 0.70 SLC2A1 (0.44) SLC2A1HDAC8KDM4E
SCHEMBL9779097 0.70 SLC2A1 (0.47) SLC2A1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447703-A1 Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine THE WELLCOME FOUNDATION LIMITED (GB) 1991-09-25 EP claimed
WO-1991014688-A1 HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE THE WELLCOME FOUNDATION LIMITED (GB) 1991-10-03 WO disclosed
EP-0447703-A1 Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine THE WELLCOME FOUNDATION LIMITED (GB) 1991-09-25 EP disclosed