Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044207 | 0.79 | ATM (0.55) | ATP4AATP4BKDM4EHSD17B10RAB9A | |
| SCHEMBL13302161 | 0.79 | MAPT (0.43) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL17831841 | 0.77 | SLC6A4 (0.47) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL29533760 | 0.75 | SLC6A4 (0.55) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL29777537 | 0.74 | ATM (0.56) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL12376 | 0.74 | ATM (0.56) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL18392203 | 0.73 | MEN1 (0.54) | SLC6A4KDM4EHSD17B10LMNAMEN1 | |
| SCHEMBL5439985 | 0.72 | SLC6A4 (0.54) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| SCHEMBL12135116 | 0.72 | PIM1 (0.51) | HTR1DHTR2ASLC6A4HTR1AHTR7 | |
| Ammonia Solution, Strong SCHEMBL23704299 | 0.72 | ATM (0.54) | HTR1DHTR2ASLC6A4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013071-A1 | NOVEL TRISUBSTITUTED PYRROLS, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-05 | — | — | WO | disclosed |