Phenolphthalein

Phenolphthalein

SCHEMBL9755053

CO.O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.93
LMNA P02545 4/20 0.93
MEN1 O00255 3/20 0.93
KMT2A Q03164 3/20 0.93
TDP1 Q9NUW8 3/20 0.93
SMN1; SMN2 Q16637 2/20 0.93
GPR55 Q9Y2T6 2/20 0.93
TYMS P04818 2/20 0.93
ALDH1A1 P00352 1/20 0.93
ESR1 P03372 1/20 0.93
TP53 P04637 1/20 0.93
CYP3A4 P08684 1/20 0.93
ALOX15 P16050 1/20 0.93
TSHR P16473 1/20 0.93
ESR2 Q92731 1/20 0.93
HSD17B10 Q99714 1/20 0.93
CFTR P13569 1/20 0.69
GOPC Q9HD26 1/20 0.69
HSP90AA1 P07900 2/20 0.68
POLB P06746 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenolphthalein SCHEMBL29362413 0.97 MAPT (1.00) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL27670 0.97 MAPT (1.00) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL6139696 0.97 MAPT (1.00) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL7479687 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL5958114 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL23929043 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL28007771 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL4749522 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL3420446 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1
Phenolphthalein SCHEMBL951288 0.95 MAPT (0.97) MAPTLMNAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061619-B Mutant gene TyrA related to phenol release amount of smoke 中国烟草总公司郑州烟草研究院 2022-06-24 CN disclosed
CN-113174395-B Mutant gene DHQ-SDH1 related to smoke phenol release amount 中国烟草总公司郑州烟草研究院 2022-06-24 CN disclosed
CN-113174395-A Mutant gene DHQ-SDH1 related to smoke phenol release amount 中国烟草总公司郑州烟草研究院 2021-07-27 CN disclosed
CN-113061619-A Mutant gene TyrA related to phenol release amount of smoke 中国烟草总公司郑州烟草研究院 2021-07-02 CN disclosed
CN-101812161-B Polyethylene bonding resin and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2011-11-09 CN disclosed
CN-101812161-A Polyethylene bonding resin and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2010-08-25 CN disclosed
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 WO disclosed
WO-1991002040-A1 CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-02-21 WO disclosed