Methacrylic Acid

Methacrylic Acid

SCHEMBL9755535

C=C.C=C(C)C(=O)O.Nc1cc(N)cc(C(=O)O)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.45
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
DDO Q99489 1/20 0.42
TDP1 Q9NUW8 2/20 0.37
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA7 P43166 3/20 0.37
CA9 Q16790 3/20 0.37
CA14 Q9ULX7 3/20 0.37
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL29067611 0.87 KDM4E (0.52) TPMTKDM4EALDH1A1MEN1KMT2A
Methacrylic Acid SCHEMBL9693555 0.86 TPMT (0.37) TPMTKDM4EALDH1A1MEN1KMT2A
SCHEMBL109155 0.82 KDM4E (0.56) TPMTKDM4EALDH1A1MEN1KMT2A
SCHEMBL2724113 0.82 TPMT (0.46) TPMTKDM4EALDH1A1MEN1KMT2A
Water SCHEMBL2806532 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL4295557 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A
SCHEMBL1477467 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL2810739 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A
SCHEMBL1478628 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A
SCHEMBL2888306 0.80 KDM4E (0.54) TPMTKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3059031-A None JP disclosed
JP-3059034-A None JP disclosed
JP-H0359034-A PRODUCTION OF POLYIMIDE RESIN HITACHI CHEM CO LTD 1991-03-14 JP disclosed
JP-H0359031-A POLYIMIDOISOINDOLOQUINAZOLINEDIONE AND PRODUCTION OF ITS PRECURSOR HITACHI CHEM CO LTD 1991-03-14 JP disclosed