SCHEMBL9755699

SCHEMBL9755699

O=C1C=Cc2c(occc2=O)C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
FTO Q9C0B1 2/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3221410 0.75 GSK3A (0.42) GSK3AGSK3B
SCHEMBL18602818 0.71 CA1 (0.34) FTOKDM4ELMNAMAOAMAOB
SCHEMBL7915034 0.67 MAPT (0.48) GSK3AGSK3BFTOKDM4EMAOA
SCHEMBL15676518 0.64 CA1 (0.33)
SCHEMBL15914282 0.63 GSK3A (0.42) GSK3AGSK3B
SCHEMBL277815 0.60
SCHEMBL9559365 0.57 GSK3A (0.40) GSK3AGSK3B
SCHEMBL1317863 0.57 GSK3A (0.40) GSK3AGSK3BKDM4ELMNAMAOA
SCHEMBL17414875 0.57 GSK3A (0.53) GSK3AGSK3B
SCHEMBL19245640 0.56 KDM4E (0.32) FTOKDM4ELMNAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0248420-B1 BENZOPYRAN DERIVATIVES DAIICHI SEIYAKU CO., LTD. (JP) 1991-09-18 EP disclosed