SCHEMBL9755786

SCHEMBL9755786

C=CCNC(Cc1ccccc1)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.46
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
MMP7 P09237 1/20 0.44
HPGDS O60760 4/20 0.44
CAPN1 P07384 1/20 0.43
CTSB P07858 1/20 0.43
ELANE P08246 1/20 0.43
FCER2 P06734 2/20 0.42
MMP1 P03956 1/20 0.42
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755788 1.00 EPHX1 (0.46) EPHX1MMP2MMP3MMP7HPGDS
SCHEMBL972348 0.87 MME (0.50) MMP2
SCHEMBL972349 0.87 MME (0.50) MMP2
Hydrochloric Acid SCHEMBL8133188 0.86 MME (0.49) MMP2
Hydrochloric Acid SCHEMBL8133191 0.86 MME (0.49) MMP2
Fluoride SCHEMBL29086588 0.84 MME (0.48) MMP2
SCHEMBL8745469 0.83 EPHX1 (0.45) EPHX1HPGDSCAPN1CTSBELANE
SCHEMBL6591455 0.82 ATM (0.55) CA12CA1CA9
SCHEMBL6591450 0.82 ATM (0.55) CA12CA1CA9
SCHEMBL29086585 0.82 MME (0.46) MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991019733-A1 DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS ABBOTT LABORATORIES (US) 1991-12-26 WO disclosed